Simparica TRIO for Dogs

Simparica Trio – Broad-Spectrum Treatment for Dogs

Are you concerned about your dog's protection from fleas, ticks, heartworms, and intestinal worms? Simparica Trio for Dogs is the solution you have been searching for. According to Zoetis USA, it is the #1 vet-prescribed combination preventive, offering comprehensive protection against both internal and external parasites. This flea, tick & worm treatment for dogs comes in a delicious, pork liver-flavored, chewable form that dogs love. Additionally, it can be administered with or without food, offering flexible administration options.

Simparica Trio, an all-in-one treatment for dogs, is the first product to combine a trio of active ingredients (sarolaner, moxidectin, and pyrantel) in one chew. It is the only combination dog formula proven to kill 6 species of ticks, ensuring your dog stays tick-safe throughout the year. Just one Simparica Trio tasty chew a month protects your furry friend against all common parasites. It's simple, effective, and reliable!

Recommended For:

• Puppies & dogs.
• Simparica Trio is recommended for puppies and dogs from 8 weeks of age and weighing at least 2.8 lbs.

Simparica Trio Coverage:

• Prevents heartworm disease caused by Dirofilaria immitis.
• Treats & controls roundworm and hookworm infections.
• Kills adult fleas before they can lay eggs.
• Treats and prevents flea infestations.
• Improves signs of flea allergy dermatitis.
• Prevents flea and tapeworm (Dipylidium caninum) infections.
• Treats & controls tick infestations (lone star tick, Gulf Coast tick, American dog tick, black-legged tick, brown dog tick, and Asian longhorned tick).
• Indicated for the prevention of Lyme disease (Borrelia burgdorferi) infections as a result of killing black-legged vector ticks.

Active Ingredients:

Sarolaner, Moxidectin, Pyrantel.

Why Should You Buy Simparica Trio Flavored Chew?

• #1 Vet-prescribed combination preventive that lasts a month long without losing effectiveness.
• Tasty pork liver-flavored chewable form allows fuss-free, easy administration.
• The only dog parasite preventive that combines three active ingredients in one chew.
• The first canine treatment to protect against six different tick species.
• A single chew per month protects against both internal and external parasites.
• Improves clinical signs of flea allergy dermatitis (FAD).
• Indicated for the prevention of Lyme disease infections as a direct result of killing black-legged ticks.

How Does Simparica Trio For Dogs Work?

Simparica Trio contains sarolaner, moxidectin, and pyrantel as the active ingredients. After administration, the chew releases these active ingredients into the dog's bloodstream. The formula is distributed to tissue fluids under the dog's skin. As soon as parasites take the blood meal from the treated dog, they ingest the formula.

Sarolaner obstructs the neuromuscular activity, leading to death in insects. It treats and prevents flea infestations and treats and controls tick infestations. Moxidectin interferes with parasites' neurotransmission, resulting in paralysis and death, thus providing protection from heartworm disease. Pyrantel acts as a depolarizing, neuromuscular-blocking agent in exposed parasites. This causes paralysis and death or expulsion of the organisms, thus treating and controlling roundworms and hookworms.

Laboratory studies suggest that a single dose of Simparica Trio is 100% effective in preventing the development of heartworm disease. According to a lab study, the chews began killing fleas at four hours and started killing black-legged ticks within eight hours. It provided 100% flea efficacy at eight hours after administration and reduced the number of live ticks by more than 94% within 24 hours of infestation.

• Administer Simparica Trio Chew orally as a single dose at monthly intervals or as directed by your veterinarian.
• It can be administered with or without food.
• After treatment, observe the dog for some time to ensure the dog consumes the complete dose.
• If you miss a dose, give one dose and resume the monthly dosing schedule.
• For flea, tick and flea tapeworm protection, you can begin your dog's treatment with Simparica Trio at any time of the year.
• For heartworm prevention, administer it year-round. It should be administered at least within one month after the dog's first exposure to mosquitoes and continuing until at least one month after the dog’s last seasonal exposure.
• For continuous, year-round protection, continue treating your dog with Simparica Trio the entire year without interruption.

Simparica Trio Dosing Guide:

Simparica Trio Chew is for dogs only. This treatment is not for use in humans or any other animal species. You should keep these chews out of the reach of children, uninformed people, and pets. In case of accidental ingestion, immediately consult a physician.

Before administration, test your dogs for existing heartworm infections and treat infected dogs to remove adult heartworms at the vet's recommendation. The safe use of Simparica Trio has not been evaluated in pregnant, breeding, or lactating dogs.

Sarolaner, one of the active ingredients in the treatment, belongs to the isoxazoline class. Use Simparica Trio with caution in dogs with a history of seizures or neurologic disorders. It should not be used in puppies and dogs under 8 weeks of age.

In field studies, Simpairca Trio was used with veterinary treatments, including vaccines, anthelmintics, antimicrobials, antiprotozoals, analgesics, NSAIDs, and anesthetic agents without any adverse reactions.

Storage Guide:

• Store at or below 30°C (86°F).